A taxi from the airport to the hotel will cost around 30 EUR. By public transport from the airport, take S-Bahn train S8 direction Hanau and alight at Ostendstrasse station. Then go upstairs to the tram station and take tram 11, direction "Fechenheim, Schiesshüttenstrasse", get off at "Osthafenplatz", cross the street at the traffic lights, turn to the left and go back about 100 metres. Then turn to the right in front of Stones Café and you will see the hotel.
From the airport take the motorway towards Frankfurt. At the Ofrenbach Crossing take exit 14 and follow signs to the City Centre (Stadtmitte), turn left at the 4th set of traffic lights before arriving at the hotel.